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ADME Senior Scientist


Boston, MA
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Job Details

Job Title: ADME Senior Scientist  - PHA001382

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its 125-year legacy. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases. 
Merck is a global health care leader with a diversified portfolio of prescription medicines, vaccines and consumer health products, as well as animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.

Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of people like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.

This position will contribute to Merck's drug discovery and clinical development efforts in the Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism (PPDM) at MRL Boston. The successful candidate will have a passion for generating high quality in vitro PPDM data for use by project teams across a range of therapeutic areas. As well as performing assays according to standard protocols, there will be opportunities to develop novel methods to address PPDM-related questions. The successful candidate will also be involved in designing and interpreting studies utilizing in silico, in vitro or in vivo approaches to improve our success in inventing differentiated medicines.

  • Bachelor’s degree with 7 years relevant experience, Master’s degree with 4 years relevant experience, or a Ph.D. Appropriate subjects for highest degree include biochemistry, chemistry, pharmacology or chemical engineering.

  • Desire to perform and interpret in vitro drug metabolism studies
  • Expertise in bioanalysis using LC-MS/MS
  • In-depth knowledge of drug metabolism and pharmacokinetics
  • Enthusiasm to learn more about drug discovery and development
  • Track record of successful leadership
  • Excellent communication and collaboration skills

  • Experience of working within a research-driven pharmaceutical company
  • Experience in peptide and/or biologics drug discovery or development
  • Familiarity with PKPD concepts and practice

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life. If you need an accommodation for the application process please email us at
Search Firm Representatives Please Read Carefully: 
Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity.  Please, no phone calls or emails.  All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck.  No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.
For more information about personal rights under Equal Employment Opportunity, visit:

Job Pharmacokinetics/Drug Metab

Primary Location NA-US-MA-Boston

Other Locations 

Employee Status Regular

Number Of Openings 1

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