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Formulations Protein Biophysical Scientist (MS/PHD) (014251W-01)

DuPont Industrial Biosciences

Palo Alto, California
Job Type:
Job Status:
Full Time
DuPont Industrial Biosciences
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Job Details

The Formulations Team at DuPont Industrial Biosciences is looking for an outstanding protein biophysicist to work in a collaborative environment characterizing macromolecules to support the development of enzyme products. The individual should have strong, in-depth technical expertise with protein biophysical characterization techniques including but not limited to UV-Vis-, IR- and Fluorescence-Spectroscopy, DLS, SLS, ITC, DSC, DSF, CD, MST, molecular and electrostatic computational modeling at high protein concentrations as applied to formulated product environments. In addition, the candidate should have both fundamental and applied understanding on interactions between biologically active proteins, and salts, low molecular weight compounds such as sugars and polyols, and non-protein macromolecules in matrices with both low and high water content. The successful candidate will have demonstrated independent and creative research, excellent design of experiments, execution of plans, interpretation of results and troubleshooting of methodologies.  In addition, the candidate will have the ability to work collaboratively in a matrix environment with the ability to train, mentor and guide junior scientists in their independent efforts. This person will be based in Palo Alto, CA or Wilmington, DE.


Responsibilities include:

  • Develop and execute biochemical and biophysical assays to support formulation development efforts
  • Apply computational tools to gain insight on excipient selection
  • Support mechanistic understanding of formulated products to help refine formulation space
  • Hands-on work in the lab
  • Excellent analytical and communication skills, and proven ability to function well in a matrix organization pursuing team objectives
  • High attention to detail


Ph.D. in biophysics, biochemistry or closely related field is preferred. M.S. with equivalent experience.


DuPont is an equal opportunity employer and an E-Verify employer


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