Sign In
 [New User? Sign Up]
Mobile Version

Scientific Researcher/Senior Scientific Researcher - Biotransformation

Genentech


Location:
South San Francisco, California
Date:
01/25/2018
2018-01-252018-02-24
Job Type:
Employee
Job Status:
Full Time
  •  
  • Save Ad
  • Email Friend
  • Print
  • Research Salary

Job Details

Join a Team that Lives to Improve Lives

People come to Genentech from across disciplines and across the world to solve our most challenging medical conditions. You’ll find inspiration in our passion for biotechnology, our purpose to positively impact the lives of millions of patients and our dedication to our people. Joining Genentech means being part of a tradition of inquiry that will change the world. It means embracing our failures as much as our successes. It requires a willingness to look beyond the edge of what's possible. And a focus on doing the day-to-day work that makes great science happen.

The following opportunity exists in our South San Francisco, CA headquarters:

Scientific Researcher/Senior Scientific Researcher - Biotransformation

Description

The department of Drug Metabolism and Pharmacokinetics (DMPK) at Genentech is seeking a Scientific Researcher or Senior Scientific Researcher with hands-on LC/MS experience and proven abilities in determining the biotransformation pathways of drugs by drug metabolizing enzymes. Primary responsibilities include:

  • profiling and identifying drug metabolites in in vitro and in vivo biological matrices using HPLC with radiometric detection and LC-MS/MS

  • designing, executing and reporting biotransformation studies to support drug development and regulatory filings.


The DMPK group is dedicated to enabling the discovery, development and
commercialization of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion and pharmacokinetic properties of small molecule drug candidates. We accomplish this through the application of state of the art technologies and sciences of bioanalysis drug metabolism, drug transport and pharmacokinetics. The DMPK group works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize leads, select clinical candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.

Who You Are

We are seeking applicants for this position with the following qualifications:

  • BS/MS degree in chemistry, biochemistry, pharmaceutical sciences or other relevant discipline

  • Hands-on experience with LC-MS and/or drug metabolism; 5+ years of experience in both LC-MS and drug metabolism with expertise in sample preparation and analysis, including metabolite structure elucidation by MS/MS, is required for the Senior Scientific Researcher level

  • Experience using radiolabels, conducting regulatory filing studies, and writing scientific reports preferred

  • Capable of working independently

  • Good written and verbal communication skills

A Job with Benefits Beyond the Benefits

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

Powered ByLogo

Featured Jobs[ View All ]