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Senior Scientist- Chemistry, Capabilities and Screening


NJ-Kenilworth, NJ
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Job Details

Job Title: Senior Scientist- Chemistry, Capabilities and Screening  - PHA001385


Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases. 

As a Sr Scientist you will be responsible for, but not limited to:

  • Chemistry Capabilities & Screening (CC&S) is seeking a highly motivated and creative scientist to fill the position of Senior Scientist and join our team of experienced and accomplished colleagues. Situated in the Screening & Compound Profiling (S&CP), the individual will have responsibilities, including:
  • Use molecular biology expertise to develop various display screening platforms to support small molecule and peptide discovery efforts  
  • Collaborate with project teams and chemistry to continue developing and optimizing the screening platforms to enable identification of better differentiation of molecules to increase the quality of drug candidates
  • Coordinate the execution of small molecule and peptide hit identification campaigns 
  • Being an internal champion for display platforms 
  • Act as liaison on projects and S&CP
  • Maintain a strong, external scientific reputation for the S&CP department through publications & presentations



  • PhD and Postdoc in a life sciences discipline (Biochemistry, Molecular Pathology, Chemical Biology etc.) AND/OR B.Sc./M.Sc. with at least five (5) years hands-on experience in display technologies. 


  • Demonstrated hands on experience and knowledge in molecular biology
  • Experienced in the development and optimization  of display screening platforms for small molecule and  peptide hits identification
  • Strong interpersonal, verbal and written communication skills
  • Ability to execute within a matrixed organization


  • Experienced in the development and optimization of display technologies, including but not limited to phage, mRNA, cDNA, ribosome display
  • Experience with unnatural amino acid incorporation 
  • Experience with linker chemistry for cyclization 

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life. 


If you need an accommodation for the application process please email us at


Search Firm Representatives Please Read Carefully: 

Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity.  Please, no phone calls or emails.  All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck.  No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.


For more information about personal rights under Equal Employment Opportunity, visit:




Job Pharmacology - DPS

Primary Location NA-US-NJ-Kenilworth

Other Locations 

Employee Status Regular

Number Of Openings 1

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