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Senior Scientist – Molecular Discovery


Palo Alto, CA
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Job Details

Job Title: Senior Scientist – Molecular Discovery  - BIO004883


Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases. 

We are seeking an experienced Senior Scientist to join our Palo Alto site to support Merck's antibody discovery programs. Primary responsibilities of this position include antibody affinity determination and characterization of various protein-ligand interactions to support discovery, QC and engineering. The selected individual will have the opportunity to work with a wide array of scientists from different departments and functional areas, using latest technologies as well as novel approaches, and make significant contributions towards Merck’s antibody discovery efforts.

Candidate is expected to be able to analyze, interpret and present data at group and departmental meetings, as well as write internal and external documents on technical and scientific findings.


  • BS/BA with at least 8 years, MS/MA with at least 6 years or PhD with 3 postdoctoral years of relevant experience in characterization and analysis of proteins interactions.

  • Must have at least 3 years of hands on experience using SPR instruments such BIAcore or ProteOn. Additional experience using KinExA, MSD, Octet or similar other platforms is helpful.
  • Must have at least 3 years of experience working with proteins or antibodies in the context of drug discovery or protein engineering.
  • Presenting in scientific meetings to communicate results and address questions.
  • Demonstrated collaborative experience working across organizations.
  • Demonstrated ability to tackle multiple projects and meet aggressive timelines.

  • Experience working with high-throughput methods and automation.
  • Experience working with cell-based binding assays.
  • Experience working with membrane proteins.

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life. If you need an accommodation for the application process please email us at


Search Firm Representatives Please Read Carefully: 

Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity.  Please, no phone calls or emails.  All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck.  No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.


For more information about personal rights under Equal Employment Opportunity, visit:




Job Biology-Discovery

Primary Location NA-US-CA-Palo Alto

Other Locations 

Employee Status Regular

Number Of Openings 1

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