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Senior Scientist


Rahway, NJ
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Job Details

Job Title: Senior Scientist  - CHE005375

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its 125-year legacy. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases. 

This position is for a senior scientist to be a key member of a team responsible for the physicochemical characterization of pharmaceutical materials, including small molecule active pharmaceutical ingredients (API), process, and in some cases drug-product intermediates. Responsibilities include characterization of amorphous and crystalline phases and solutions as well as performing crystallizations using focused manual experiments and/or screening platforms for identification of phases in the support of the discovery and development of pharmaceuticals.  Additional responsibilities will include the design and execution of PAT based experiments to enable unique process analyses targeting mechanistic understanding to inform process development.  

The ideal candidate will be expected to play a leading role in the development of novel techniques for the physicochemical characterization of the surface and bulk of pharmaceutical materials in areas such as advanced spectroscopy, microscopy, scattering and diffraction and to identify and contribute to efforts for adopting new technologies and approaches related to PAT. While the majority of materials will be small molecules, there will be opportunities to perform biophysical characterization of complex molecules such as synthetic peptides, bioconjugates and small proteins. 

  • BS/MS/PhD  in Physical Chemistry, Physical Organic Chemistry, Materials Science, Pharmaceutics, Chemical Engineering, Chemistry or related fields
  • BS with 10 years experience OR MS with 5 years experience OR Ph.D. with experience in the pharmaceutical industry
  • Knowledge of physicochemical characterization of organic and/or inorganic materials
  • Knowledge of Process Analytical Technology method/model development, including chemometrics and multivariate data analysis (MVDA) 
  • Strong mathematical skills and experience with mathematical programming
  • Experience in biophysical characterization 
  • Experience with powder properties and surface characterization tools (such as particle size, surface area, porosity, surface energetics, wettability, etc.) 
  • Experience in characterization of solids and/or liquids using analytical techniques such as powder X-ray diffraction, thermal analysis (DSC, TGA, and solution), spectroscopic methods (Raman, IR, and NMR), microscopy (light and electron) and/or dynamic vapor sorption desirable.

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life. 

If you need an accommodation for the application process please email us at

Search Firm Representatives Please Read Carefully:  
Merck is not accepting unsolicited assistance from search firms for this employment opportunity.  Please, no phone calls or emails.  All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck.  No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.
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Job Chemistry

Primary Location NA-US-NJ-Rahway

Other Locations 

Employee Status Regular

Number Of Openings 1

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