Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology we collaborate to discover the next medical breakthrough.
The Biophysical Characterization group in Pharmaceutical Sciences is seeking a talented and highly self-motivated scientist with solid experience in biotherapeutics characterization. As a Senior Scientist, you will be responsible for characterization of biotherapeutic drug products with focus on higher order structure. You will be working in a collaboratively team environment to support both early and late stage formulation development. You will be responsible for building fundamental formulation stability understanding to ensure formulation robustness. Additional responsibilities include writing technical reports, presenting technical data, and project management. The selected individual will have the opportunity to work with a wide array of scientists from our different divisions and make significant contributions towards our development efforts of biotherapeutics.
Education Minimum Requirement:
Ph.D. in Biophysics, Biochemistry, Chemistry, Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences or related discipline with 0-4 years’ experience.
Required Experience and Skills:
Fundamental understanding of protein science, protein/peptide stability, and protein-protein interactions
Experience with biophysical and biochemical techniques for biotherapeutics characterization.
Self-motivated with an outstanding scientific track-record.
Excellent interpersonal and communication skills, both verbal and written.
Track-record of independent problem-solving and application of advanced innovative scientific approaches.
Desire and willingness to learn and contribute.
Excellent organizational skills to multi-task and manage multiple projects.
Desired Experience and Skills -
Experience with molecular modeling.
Experience with BioNMR and/or Mass Spectrometry.
Experience with formulation development and analytical method development.
Internal Number: R3843
Pharmaceutical Sciences & Global Clinical Supply (Pharm. Sci. &GCS) undertakes a wide range of drug development activities to transform scientific concepts into innovative pharmaceutical products.
Pharm. Sci. & GCS are two Merck Research Laboratories (MRL) organizations that are passionately committed to setting the standard for our industry at multiple levels, including: 1) executing innovative and efficient pharmaceutical development, thereby maximizing patient value; 2) developing robust formulations, processes, and analytical methods to support commercialization of our products; 3) operating an agile, responsive, reliable, and cost-effective clinical supply chain; and 4) creating corporate value through product life cycle management (LCM) and intellectual property development.