Moderna’s Bioanalytics team is looking for Scientist/ Principal Research Associate with strong hands-on experiences in bioanalytical RT-qPCR/qPCR . The individual should have recent experiences in processing and analysis of wide range of molecules such as proteins, peptides, lipids, glycans, mRNA etc. The role will be supporting method development for non-clinical studies of development candidates applying cutting-edge RT-qPCR/qPCR/ddPCR techniques towards mechanistic and quantitative assessment of Moderna’s mRNA therapeutics. The candidate must thrive in scientifically stimulating and fast paced environment with high expectations. Independent method development, data integrity, ability to troubleshoot, collaborate with cross functional teams, respect for peers/colleagues, excellent work ethic and setting the bar high are key values to thrive in our Team. 

The candidate must thrive in a fast pace environment with high expectations. Integrity, quality, ability to troubleshoot issues, creative, bold, curiosity, collaborative spirit, respect for people, exemplary work ethic and setting the bar high are key values to thrive in our Team.

Here’s What You’ll Do:

• Method development, method optimization, fit-for-purpose qualification to support all Therapeutic Programs  

• Develop, optimize, qualify, and run bioanalytical RT-qPCR/qPCR/ddPCR methods for quantitation of various mRNA in drug products.  

• Coordinate with external CROs on method development and qualification  

• Perform method transfer to internal and external stakeholders for qualification / validation  

• Review and author relevant protocols, and reports 

• Support nonclinical in-vivo studies to evaluate PK/TK, safety, and efficacy of Moderna’s drug candidates 

• Work closely with colleagues in clinical development organization as well as other cross-functional groups 

• Mentor/coach junior staff on qPCR/RT-qPCR/ddPCR based methodologies.

• Provide RT-qPCR support to scientists in Nonclinical, Platform, and other groups